2pr2

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[[Image:2pr2.jpg|left|200px]]<br /><applet load="2pr2" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2pr2.jpg|left|200px]]
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caption="2pr2, resolution 2.500&Aring;" />
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'''Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.'''<br />
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==About this Structure==
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{{Structure
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2PR2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=DG1:'>DG1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PR2 OCA].
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|PDB= 2pr2 |SIZE=350|CAPTION= <scene name='initialview01'>2pr2</scene>, resolution 2.500&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=DG1:'>DG1</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9]
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|GENE= inhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
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}}
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==Reference==
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'''Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.'''
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New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP., Argyrou A, Vetting MW, Blanchard JS, J Am Chem Soc. 2007 Aug 8;129(31):9582-3. Epub 2007 Jul 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17636923 17636923]
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==About this Structure==
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2PR2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PR2 OCA].
[[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]
[[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:32:13 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:19:23 2008''

Revision as of 16:19, 20 March 2008

Image:2pr2.jpg


PDB ID 2pr2

Drag the structure with the mouse to rotate
, resolution 2.500Å
Ligands:
Gene: inhA (Mycobacterium tuberculosis)
Activity: [acyl-carrier-protein_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number 1.3.1.9
Coordinates: save as pdb, mmCIF, xml



Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.


About this Structure

2PR2 is a Single protein structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. [[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]

Page seeded by OCA on Thu Mar 20 18:19:23 2008

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