4uec

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'''Unreleased structure'''
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==complex of d. melanogaster EIF4E with EIF4G and CAP analog==
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<StructureSection load='4uec' size='340' side='right' caption='[[4uec]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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The entry 4uec is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uec]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEC FirstGlance]. <br>
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Authors: PETER, D., WEICHENRIEDER, O.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MGT:7N-METHYL-8-HYDROGUANOSINE-5-TRIPHOSPHATE'>MGT</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ue8|4ue8]], [[4ue9|4ue9]], [[4uea|4uea]], [[4ueb|4ueb]], [[4ued|4ued]]</td></tr>
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Description: complex of d. melanogaster EIF4E with EIF4G and CAP analog
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uec RCSB], [http://www.ebi.ac.uk/pdbsum/4uec PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IF4E_DROME IF4E_DROME]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.<ref>PMID:8663200</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Peter, D]]
[[Category: Peter, D]]
[[Category: Weichenrieder, O]]
[[Category: Weichenrieder, O]]
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[[Category: 4e binding protein]]
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[[Category: Cap binding protein]]
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[[Category: Gene regulation]]
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[[Category: Translation]]
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[[Category: Translation initiation]]

Revision as of 14:04, 25 February 2015

complex of d. melanogaster EIF4E with EIF4G and CAP analog

4uec, resolution 2.40Å

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