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4q9j

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'''Unreleased structure'''
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==P-glycoprotein cocrystallised with QZ-Val==
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<StructureSection load='4q9j' size='340' side='right' caption='[[4q9j]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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The entry 4q9j is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4q9j]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q9J FirstGlance]. <br>
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Authors: McGrath, A.P., Szewczyk, P., Chang, G.
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=30F:(2Z)-2-AMINO-3-SELANYLPROP-2-ENOIC+ACID'>30F</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q9h|4q9h]], [[4q9i|4q9i]], [[4q9k|4q9k]], [[4q9l|4q9l]]</td></tr>
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Description:
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q9j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q9j RCSB], [http://www.ebi.ac.uk/pdbsum/4q9j PDBsum]</span></td></tr>
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[[Category: Mcgrath, A.P]]
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</table>
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[[Category: Szewczyk, P]]
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== Function ==
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[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Xenobiotic-transporting ATPase]]
[[Category: Chang, G]]
[[Category: Chang, G]]
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[[Category: McGrath, A P]]
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[[Category: Szewczyk, P]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Membrane protein]]
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[[Category: Transporter]]

Revision as of 11:34, 4 March 2015

P-glycoprotein cocrystallised with QZ-Val

4q9j, resolution 3.60Å

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