4w51

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'''Unreleased structure'''
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==T4 Lysozyme L99A with No Ligand Bound==
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<StructureSection load='4w51' size='340' side='right' caption='[[4w51]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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The entry 4w51 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4w51]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W51 FirstGlance]. <br>
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Authors: Merski, M., Shoichet, B.K., Eidam, O., Fischer, M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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Description: T4 Lysozyme L99A with No Ligand Bound
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w51 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w51 RCSB], [http://www.ebi.ac.uk/pdbsum/4w51 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Merski, M]]
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== Function ==
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[[Category: Fischer, M]]
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[[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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[[Category: Shoichet, B.K]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Lysozyme]]
[[Category: Eidam, O]]
[[Category: Eidam, O]]
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[[Category: Fischer, M]]
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[[Category: Merski, M]]
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[[Category: Shoichet, B K]]
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[[Category: Hydrolase]]

Revision as of 13:20, 1 April 2015

T4 Lysozyme L99A with No Ligand Bound

4w51, resolution 1.45Å

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