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4z18
From Proteopedia
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| - | ''' | + | ==CRYSTAL STRUCTURE OF HUMAN PD-L1== |
| - | + | <StructureSection load='4z18' size='340' side='right' caption='[[4z18]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4z18]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z18 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z18 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fn3|3fn3]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z18 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4z18 RCSB], [http://www.ebi.ac.uk/pdbsum/4z18 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[Category: Almo, S | + | [[http://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN]] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref> |
| - | [[Category: Fedorov, A | + | == References == |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Almo, S C]] | ||
| + | [[Category: Fedorov, A A]] | ||
| + | [[Category: Fedorov, E V]] | ||
[[Category: Hillerich, B]] | [[Category: Hillerich, B]] | ||
| - | [[Category: | + | [[Category: Samantha, D]] |
| + | [[Category: Seidel, R D]] | ||
| + | [[Category: Dimer]] | ||
| + | [[Category: Human pd-l1]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Uncomplexed]] | ||
Revision as of 13:04, 15 April 2015
CRYSTAL STRUCTURE OF HUMAN PD-L1
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