Lysine-specific histone demethylase
From Proteopedia
(Difference between revisions)
m (Lysine-specific histone demethylase 1 moved to Lysine-specific histone demethylase: requested by Editor) |
Revision as of 08:37, 4 May 2015
Lysine-specific histone demethylase 1 (LSD1) is a flavin-dependent oxidase that catalyzes the removal of methyl groups from mono- and dimethylated lysine 4 of histone H3. LSD1 is a nuclear homolog of amine oxidase. It functions as histone demethylase and transcriptional corepressor. LSD1 demethylation occurs via a reaction which produces formaldehyde. LSD1 is a component of transcriptional corepressor complex which also contains CoREST (corepressor of element-1-silencing transcription factor).
3D structures of lysine-specific histone demethylase 1
Updated on 04-May-2015
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
