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4pc6

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'''Unreleased structure'''
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==Elongation factor Tu:Ts complex with bound GDPNP==
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<StructureSection load='4pc6' size='340' side='right' caption='[[4pc6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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The entry 4pc6 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4pc6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PC6 FirstGlance]. <br>
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Authors: Thirup, S.S.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pc1|4pc1]], [[4pc2|4pc2]], [[4pc3|4pc3]]</td></tr>
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Description: Elongation factor Tu:Ts complex with bound GDPNP
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pc6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pc6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pc6 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Thirup, S.S]]
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== Function ==
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[[http://www.uniprot.org/uniprot/B1X6I9_ECODH B1X6I9_ECODH]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118] [[http://www.uniprot.org/uniprot/C9QRL8_ECOD1 C9QRL8_ECOD1]] Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.[HAMAP-Rule:MF_00050][RuleBase:RU000642]
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__TOC__
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</StructureSection>
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[[Category: Thirup, S S]]
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[[Category: Elongation factor]]
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[[Category: G:gef:nucleotide complex]]
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[[Category: Protein synthesis]]
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[[Category: Translation]]

Revision as of 12:56, 6 May 2015

Elongation factor Tu:Ts complex with bound GDPNP

4pc6, resolution 2.20Å

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