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4pc7
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Elongation factor Tu:Ts complex in a near GTP conformation.== |
| - | + | <StructureSection load='4pc7' size='340' side='right' caption='[[4pc7]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4pc7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PC7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PUL:(1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOXACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL+6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE'>PUL</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pc1|4pc1]], [[4pc2|4pc2]], [[4pc3|4pc3]], [[4pc6|4pc6]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pc7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pc7 RCSB], [http://www.ebi.ac.uk/pdbsum/4pc7 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: Thirup, S | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/EFTU1_ECOLI EFTU1_ECOLI]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118] May play an important regulatory role in cell growth and in the bacterial response to nutrient deprivation.[HAMAP-Rule:MF_00118] [[http://www.uniprot.org/uniprot/EFTS_ECOLI EFTS_ECOLI]] Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.[HAMAP-Rule:MF_00050] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Thirup, S S]] | ||
| + | [[Category: Elongation factor]] | ||
| + | [[Category: G:gef:nucleotide complex]] | ||
| + | [[Category: Protein synthesis]] | ||
| + | [[Category: Translation]] | ||
Revision as of 12:56, 6 May 2015
Elongation factor Tu:Ts complex in a near GTP conformation.
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