Phosphoserine aminotransferase
From Proteopedia
(Difference between revisions)
| Line 24: | Line 24: | ||
**[[3e77]] – PSAT + PLP – human<br /> | **[[3e77]] – PSAT + PLP – human<br /> | ||
**[[3ffr]] – PSAT + PLP – ''Cytophaga hutchinsonii''<br /> | **[[3ffr]] – PSAT + PLP – ''Cytophaga hutchinsonii''<br /> | ||
| - | **[[3qbo]] – PSAT + PLP | + | **[[3qbo]] – PSAT + PLP <br /> |
| + | **[[2fyf]] - PSAT + PLP – ''Mycobacterium tuberculosis''<br /> | ||
*Phosphoserine aminotransferase ternary complex | *Phosphoserine aminotransferase ternary complex | ||
| - | **[[1bjo]] - EcPSAT + α-methyl-glutamate + PLP | + | **[[1bjo]] - EcPSAT + α-methyl-glutamate + PLP<br /> |
| + | **[[4xk1]] - PSAT + PLP + glutamate – ''Pseudomonas aeruginosa''<br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:42, 13 May 2015
Phosphoserine aminotransferase (PSAT) catalyzes the reversible conversion of phosphoserine and oxoglutarate to produce glutamate and 3-phosphonooxypyruvate. PSAT is part of the phosphoserine biosynthesis. Pyridoxal phosphate (vitamin B6, PLP) is a cofactor of PAT. PSAT is over-expressed in colon tumors and its inhibition is being tested as drug treatment.
3D structures of phosphoserine aminotransferase
Updated on 13-May-2015
