Plasminogen activator

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**[[1kdu]] - hTPA kringle domain – NMR<br />
**[[1kdu]] - hTPA kringle domain – NMR<br />
**[[1tpm]], [[1tpn]] - hTPA fibrin-binding domain – NMR
**[[1tpm]], [[1tpn]] - hTPA fibrin-binding domain – NMR
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 +
*Coagulase/fibrinolysin
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**[[2x55]], [[2x56]] - YpTPA – ''Yersinia pestis''<br />
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**[[2x4m]] - YpTPA (mutant)<br />
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**[[4dcb]] - YpTPA (mutant) + plasminogen peptide<br />
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*Urokinase-type plasminogen activator see [[Urokinase]]
*Urokinase-type plasminogen activator see [[Urokinase]]
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:12, 13 May 2015

Template:STRUCTURE 1a5h

Plasminogen activator (PLA) is a serine protease which converts plasminogen to plasmin. It includes Tissue PLA (TPA) which is involved in breakdown of blood clots and urokinase-type PLA Urokinase. TPA structure contains heavy and light chains (HC, LC). PLA is inhibited by PLA inhibitor 1 and 2.

Contents

3D structures of plasminogen activator

Updated on 13-May-2015


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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