This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4d60
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Structure of a dimeric Plasmodium falciparum profilin mutant== |
| - | + | <StructureSection load='4d60' size='340' side='right' caption='[[4d60]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4d60]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D60 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d60 RCSB], [http://www.ebi.ac.uk/pdbsum/4d60 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: Kallio, J | + | [[http://www.uniprot.org/uniprot/PROF_PLAFX PROF_PLAFX]] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers.<ref>PMID:19000816</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bhargav, S P]] | ||
| + | [[Category: Kallio, J P]] | ||
[[Category: Kursula, I]] | [[Category: Kursula, I]] | ||
| - | [[Category: Vahokoski, J]] | ||
[[Category: Kursula, P]] | [[Category: Kursula, P]] | ||
[[Category: Torda, A]] | [[Category: Torda, A]] | ||
| - | [[Category: | + | [[Category: Vahokoski, J]] |
| + | [[Category: Actin binding]] | ||
| + | [[Category: Domain swapping]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 12:42, 3 June 2015
Structure of a dimeric Plasmodium falciparum profilin mutant
| |||||||||||
