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4y21
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal Structure of Munc13-1 MUN domain== |
| - | + | <StructureSection load='4y21' size='340' side='right' caption='[[4y21]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4y21]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y21 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y21 RCSB], [http://www.ebi.ac.uk/pdbsum/4y21 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/UN13A_RAT UN13A_RAT]] Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. Also involved in secretory granule priming in insulin secretion.<ref>PMID:9697857</ref> <ref>PMID:11343654</ref> <ref>PMID:11792326</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kang, L J]] | ||
| + | [[Category: Ma, C]] | ||
[[Category: Rizo, J]] | [[Category: Rizo, J]] | ||
| - | [[Category: Yang, X.Y]] | ||
| - | [[Category: Xu, T]] | ||
[[Category: Sheng, Y]] | [[Category: Sheng, Y]] | ||
| - | [[Category: Wu, L.J]] | ||
[[Category: Wang, S]] | [[Category: Wang, S]] | ||
| - | [[Category: | + | [[Category: Wu, L J]] |
| - | [[Category: | + | [[Category: Xu, T]] |
| + | [[Category: Yang, X Y]] | ||
[[Category: Zhang, M]] | [[Category: Zhang, M]] | ||
| - | [[Category: Zou, W | + | [[Category: Zhang, R G]] |
| - | [[Category: | + | [[Category: Zou, W J]] |
| + | [[Category: Catchr]] | ||
| + | [[Category: Exocytosis]] | ||
| + | [[Category: Helical bundle]] | ||
Revision as of 14:10, 10 June 2015
Crystal Structure of Munc13-1 MUN domain
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Categories: Kang, L J | Ma, C | Rizo, J | Sheng, Y | Wang, S | Wu, L J | Xu, T | Yang, X Y | Zhang, M | Zhang, R G | Zou, W J | Catchr | Exocytosis | Helical bundle
