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Complement C5

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(New page: <StructureSection load='3pvm' size='340' side='right' caption='Human complement C5 complex with cobra venom factor (PDB code 3pvm)' scene=''> '''Complement C5''' (CC5) is the fifth co...)
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<StructureSection load='3pvm' size='340' side='right' caption='Human complement C5 complex (grey and pink) with cobra venom factor (green and yellow) (PDB code [[3pvm]])' scene=''>
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<StructureSection load='3pvm' size='340' side='right' caption='Human complement C5 complex with cobra venom factor (PDB code [[3pvm]])' scene=''>
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'''Complement C5''' (CC5) is the fifth component of the complement system. The complement system is part of the innate immune system. CC5 is composed of α chain (C5a) and β chain (C5b). Proteoplytic degradation of CC5 produces '''anaphylatoxin''' which is a mediator of local inflammatory process. The C terminal domain of CC5 (residues 1530-1676) is homologous to a domain in netrins and is named '''C345C'''. Activation of CC5 by C5 convertase initiates the assembly of the C5 to C9 components into the membrane attack complex.
'''Complement C5''' (CC5) is the fifth component of the complement system. The complement system is part of the innate immune system. CC5 is composed of α chain (C5a) and β chain (C5b). Proteoplytic degradation of CC5 produces '''anaphylatoxin''' which is a mediator of local inflammatory process. The C terminal domain of CC5 (residues 1530-1676) is homologous to a domain in netrins and is named '''C345C'''. Activation of CC5 by C5 convertase initiates the assembly of the C5 to C9 components into the membrane attack complex.

Revision as of 09:17, 28 June 2015

Human complement C5 complex (grey and pink) with cobra venom factor (green and yellow) (PDB code 3pvm)

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3D Structures of complement C5

Updated on 28-June-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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