Tumor necrosis factor receptor

(Difference between revisions)

Revision as of 09:39, 21 July 2015

Updated on 21-July-2015

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 '''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is  a trimeric cytokine receptor which binds TNF.  TNFR family contains several members and superfamily (TNFRSF) members.  The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br />
+*  '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β''';<br />
+*  '''TNFRSF 4''' is called '''OX40L receptor''';<br />
+*  '''TNFRSF 5''' is called '''CD40L receptor''';<br />
 *  '''TNFRSF 6''' is called '''Fas''';<br />
+*  '''TNFRSF 9''' is called '''4-1BBL''';<br />
 * '''TNFRSF 10B''' is called '''Dr5''';<br />
+*  '''TNFRSF 11''' is called '''RANKL''';<br />
+*  '''TNFRSF 11A''' is called '''RANK''';<br />
+*  '''TNFRSF 12''' is called '''TWEAK''';<br />
+*  '''TNFRSF 12A''' is called '''TWEAKR''';<br />
+*  '''TNFRSF 13''' is called '''APRIL''';<br />
+*  '''TNFRSF 13B''' is called '''BAFF or sTALL-1''';<br />
+*  '''TNFRSF 13C''' is called '''BAFF receptor''';<br />
+*  '''TNFRSF 14''' is called '''LIGHT''';<br />
 * '''TNFRSF 16''' is called '''Nerve growth factor receptor''';<br />
+* '''TNFRSF 18''' is called '''GITRL''';<br />
 * '''TNFRSF 21''' is called '''Dr6''';<br />
-* '''TNFRSF 11A''' is called '''RANK''';<br />
-* '''TNFRSF 18''' is called '''GITRL'''.
 == Disease ==