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Tumor necrosis factor receptor

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'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br />
'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br />
* '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β''';<br />
* '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β''';<br />
 +
* '''TNFRSF 3''' is called '''TNFR-III''';<br />
* '''TNFRSF 4''' is called '''OX40L receptor''';<br />
* '''TNFRSF 4''' is called '''OX40L receptor''';<br />
* '''TNFRSF 5''' is called '''CD40L receptor''';<br />
* '''TNFRSF 5''' is called '''CD40L receptor''';<br />
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* '''TNFRSF 11''' is called '''RANKL''';<br />
* '''TNFRSF 11''' is called '''RANKL''';<br />
* '''TNFRSF 11A''' is called '''RANK''';<br />
* '''TNFRSF 11A''' is called '''RANK''';<br />
 +
* '''TNFRSF 11B''' is called '''Osteoprotegerin''';<br />
* '''TNFRSF 12''' is called '''TWEAK''';<br />
* '''TNFRSF 12''' is called '''TWEAK''';<br />
* '''TNFRSF 12A''' is called '''TWEAKR''';<br />
* '''TNFRSF 12A''' is called '''TWEAKR''';<br />
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**[[3me4]] – mTNFRSF-11A extracellular domain <br />
**[[3me4]] – mTNFRSF-11A extracellular domain <br />
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*Tumor necrosis factor receptor superfamily-11B
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*Tumor necrosis factor receptor superfamily-11B (Osteoprotegerin)
**[[3urf]] – hTNFRSF-11B extracellular domain + TNFRSF-11B ligand<br />
**[[3urf]] – hTNFRSF-11B extracellular domain + TNFRSF-11B ligand<br />

Revision as of 05:48, 22 July 2015

Structure of human TNFRSF-18 extracellular domain (PDB code 2q1m).

Drag the structure with the mouse to rotate

3D structures of tumor necrosis factor receptor

Updated on 22-July-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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