4zup
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor== |
| - | + | <StructureSection load='4zup' size='340' side='right' caption='[[4zup]], [[Resolution|resolution]] 1.42Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4zup]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZUP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5XA:5-AMINO-N-HYDROXYPENTANAMIDE'>5XA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zum|4zum]], [[4zun|4zun]], [[4zuo|4zuo]], [[4zuq|4zuq]], [[4zur|4zur]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zup OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zup RCSB], [http://www.ebi.ac.uk/pdbsum/4zup PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/APHA_MYCRA APHA_MYCRA]] Acts on many types of acetylpolyamines. Has high affinity towards acetylputrescine, acetylcadaverine, acetylspermidine, and acetylspermine. Acts on L-Lys-(epsilon-acetyl)-coumarin, but has very low activity towards acetylated peptides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Christianson, D W]] | ||
[[Category: Decroos, C]] | [[Category: Decroos, C]] | ||
| - | [[Category: | + | [[Category: Acetylpolyamine amidohydrolase]] |
| + | [[Category: Arginase fold]] | ||
| + | [[Category: Enzyme-inhibitor complex]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Polyamine]] | ||
Revision as of 14:52, 29 July 2015
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
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