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4uf3

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m (Protected "4uf3" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Deerpox virus DPV022 in complex with Bim BH3==
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<StructureSection load='4uf3' size='340' side='right' caption='[[4uf3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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The entry 4uf3 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uf3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF3 FirstGlance]. <br>
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Authors: Burton, D.R., Kvansakul, M.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uf1|4uf1]], [[4uf2|4uf2]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uf3 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf3 PDBsum]</span></td></tr>
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Description: Deerpox virus DPV022 in complex with Bim BH3
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Burton, D.R]]
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[[http://www.uniprot.org/uniprot/B2L11_HUMAN B2L11_HUMAN]] Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.<ref>PMID:9430630</ref> <ref>PMID:11734221</ref> <ref>PMID:12019181</ref> <ref>PMID:11997495</ref> <ref>PMID:15147734</ref> <ref>PMID:15486195</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Burton, D R]]
[[Category: Kvansakul, M]]
[[Category: Kvansakul, M]]
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[[Category: Apoptosis]]
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[[Category: Bcl-2]]
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[[Category: Bim bh3]]
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[[Category: Deerpox virus]]
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[[Category: Dpv022]]
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[[Category: Viral protein]]

Revision as of 20:11, 5 August 2015

Deerpox virus DPV022 in complex with Bim BH3

4uf3, resolution 2.70Å

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