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4ycx
From Proteopedia
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| - | ''' | + | ==Binary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate== |
| - | + | <StructureSection load='4ycx' size='340' side='right' caption='[[4ycx]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ycx]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YCX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YCX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yd1|4yd1]], [[4yd2|4yd2]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ycx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ycx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ycx RCSB], [http://www.ebi.ac.uk/pdbsum/4ycx PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPOLM_HUMAN DPOLM_HUMAN]] Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.<ref>PMID:12640116</ref> <ref>PMID:12888504</ref> <ref>PMID:17483519</ref> <ref>PMID:17915942</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Bebenek, K]] | [[Category: Bebenek, K]] | ||
| - | [[Category: Gosavi, R | + | [[Category: Gosavi, R A]] |
| - | [[Category: Pedersen, L | + | [[Category: Kunkel, T A]] |
| - | [[Category: | + | [[Category: Moon, A F]] |
| + | [[Category: Pedersen, L C]] | ||
| + | [[Category: Dna repair]] | ||
| + | [[Category: Nhej]] | ||
| + | [[Category: Polymerase]] | ||
| + | [[Category: Transferase-dna complex]] | ||
Revision as of 20:14, 5 August 2015
Binary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate
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