4xep
From Proteopedia
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| - | ''' | + | ==Crystal Structure of F222 form of E112A/H234A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium== |
| - | + | <StructureSection load='4xep' size='340' side='right' caption='[[4xep]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xep]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XEP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gad|4gad]], [[4g9o|4g9o]], [[4ryt|4ryt]], [[4ryu|4ryu]], [[4xer|4xer]], [[4xgb|4xgb]], [[4xgp|4xgp]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xep OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xep RCSB], [http://www.ebi.ac.uk/pdbsum/4xep PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Murthy, M | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/SURE_SALTY SURE_SALTY]] Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.[HAMAP-Rule:MF_00060] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Mathiharan, Y K]] | ||
| + | [[Category: Murthy, M R.N]] | ||
| + | [[Category: Domain swapping]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Phosphatase]] | ||
| + | [[Category: Rossmann fold like]] | ||
| + | [[Category: Stationary phase survival protein]] | ||
Revision as of 11:20, 9 September 2015
Crystal Structure of F222 form of E112A/H234A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium
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