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2eyx
From Proteopedia
(Difference between revisions)
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<StructureSection load='2eyx' size='340' side='right' caption='[[2eyx]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''> | <StructureSection load='2eyx' size='340' side='right' caption='[[2eyx]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2eyx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2eyx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EYX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EYX FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2eyv|2eyv]], [[2eyw|2eyw]], [[2eyy|2eyy]], [[2eyz|2eyz]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2eyv|2eyv]], [[2eyw|2eyw]], [[2eyy|2eyy]], [[2eyz|2eyz]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eyx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2eyx RCSB], [http://www.ebi.ac.uk/pdbsum/2eyx PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eyx OCA], [http://pdbe.org/2eyx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eyx RCSB], [http://www.ebi.ac.uk/pdbsum/2eyx PDBsum]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CRK_HUMAN CRK_HUMAN]] The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.<ref>PMID:1630456</ref> <ref>PMID:11870224</ref> <ref>PMID:17515907</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2eyx" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Inagaki, F]] | [[Category: Inagaki, F]] | ||
[[Category: Kobashigawa, Y]] | [[Category: Kobashigawa, Y]] | ||
Revision as of 17:44, 10 September 2015
C-Terminal SH3 domain of CT10-Regulated Kinase
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Categories: Human | Inagaki, F | Kobashigawa, Y | Tanaka, S | Sh3 | Signaling protein
