This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4pfa
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal structure of M. tuberculosis in complex with BTO - covalent adduct== |
| - | + | <StructureSection load='4pfa' size='340' side='right' caption='[[4pfa]], [[Resolution|resolution]] 2.56Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4pfa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PFA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=N77:7-(HYDROXYAMINO)-N-(PYRIDIN-3-YLMETHYL)-5-(TRIFLUOROMETHYL)-1,3-BENZOTHIAZOLE-2-CARBOXAMIDE+3-OXIDE'>N77</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pfd|4pfd]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pfa OCA], [http://pdbe.org/4pfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pfa RCSB], [http://www.ebi.ac.uk/pdbsum/4pfa PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/DPRE1_MYCTU DPRE1_MYCTU]] Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (DPR) to yield decaprenylphosphoryl 2-keto-ribose (DPX).<ref>PMID:16291675</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cole, S]] | ||
[[Category: Neres, J]] | [[Category: Neres, J]] | ||
| + | [[Category: Panda, M]] | ||
| + | [[Category: Covalent]] | ||
| + | [[Category: Dpre1]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
Revision as of 05:28, 22 October 2015
Crystal structure of M. tuberculosis in complex with BTO - covalent adduct
| |||||||||||
