Carbonyl reductase
From Proteopedia
(Difference between revisions)
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**[[3ctm]], [[4oaq]] – CpCBR – ''Candida parapsilosis''<br /> | **[[3ctm]], [[4oaq]] – CpCBR – ''Candida parapsilosis''<br /> | ||
| - | **[[3wle]], [[4c4o]] – CpCBR + NAD<br /> | + | **[[4oaq]] – CpCBR + Zn<br /> |
| - | **[[3wlf]] – CpCBR + phenylethane diol<br /> | + | **[[3wle]], [[4c4o]] – CpCBR + NAD + Zn<br /> |
| - | **[[3wnq]] – CpCBR (mutant) + hydroxyacetophenone<br /> | + | **[[3wlf]] – CpCBR + phenylethane diol + Zn<br /> |
| + | **[[3wnq]] – CpCBR (mutant) + hydroxyacetophenone + Zn<br /> | ||
*Carbonyl reductase binary complex with NADPH | *Carbonyl reductase binary complex with NADPH | ||
Revision as of 11:24, 18 November 2015
Carbonyl reductase (CBR) catalyzes the reaction converting R-CHOH-R and NADP to R-CO-R’ and NADPH. CBR has wide substrate specificity oxidoreductase activity. CBR has similar properties to aldose reductase and aldehyde reductase.
3D structures of carbonyl reductase
Updated on 18-November-2015
