1a7s
From Proteopedia
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|PDB= 1a7s |SIZE=350|CAPTION= <scene name='initialview01'>1a7s</scene>, resolution 1.12Å | |PDB= 1a7s |SIZE=350|CAPTION= <scene name='initialview01'>1a7s</scene>, resolution 1.12Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7s OCA], [http://www.ebi.ac.uk/pdbsum/1a7s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1a7s RCSB]</span> | ||
}} | }} | ||
| Line 27: | Line 30: | ||
[[Category: Kastrup, J S.]] | [[Category: Kastrup, J S.]] | ||
[[Category: Larsen, I K.]] | [[Category: Larsen, I K.]] | ||
| - | [[Category: CL]] | ||
| - | [[Category: EOH]] | ||
| - | [[Category: NAG]] | ||
[[Category: endotoxin binding]] | [[Category: endotoxin binding]] | ||
[[Category: heparin]] | [[Category: heparin]] | ||
[[Category: serine protease homolog]] | [[Category: serine protease homolog]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:35:04 2008'' |
Revision as of 15:35, 30 March 2008
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| , resolution 1.12Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
ATOMIC RESOLUTION STRUCTURE OF HBP
Overview
Crystals of human heparin binding protein (HBP) diffract to 1.1 A when flash-frozen at 120 K. The atomic resolution structure has been refined anisotropically using SHELXL96. The final model of HBP consists of 221 amino-acid residues of 225 possible, three glycosylation units, one chloride ion, 15 precipitant ethanol molecules and 323 water molecules. The structure is refined to a final crystallographic R factor of 15.9% and Rfree(5%) of 18.9% using all data. A putative protein kinase C activation site has been identified, involving residues 113-120. The structure is compared to the previously determined 2.3 A resolution structure of HBP.
About this Structure
1A7S is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:9761855
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