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4rsn
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of the E267V mutant of cytochrome P450 BM3== |
| - | + | <StructureSection load='4rsn' size='340' side='right' caption='[[4rsn]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rsn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RSN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RSN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hf2|3hf2]], [[3m4v|3m4v]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rsn OCA], [http://pdbe.org/4rsn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rsn RCSB], [http://www.ebi.ac.uk/pdbsum/4rsn PDBsum]</span></td></tr> |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450. |
| - | [[Category: Ren, X | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Unspecific monooxygenase]] | ||
| + | [[Category: Ren, X K]] | ||
[[Category: Taylor, A]] | [[Category: Taylor, A]] | ||
| - | [[Category: Wong, L | + | [[Category: Wong, L L]] |
| - | [[Category: Zhou, W | + | [[Category: Yorke, J A]] |
| + | [[Category: Zhang, A L]] | ||
| + | [[Category: Zhang, T]] | ||
| + | [[Category: Zhou, W H]] | ||
| + | [[Category: Bifunctional p-450/nadph-p450 reductase]] | ||
| + | [[Category: Heme domain]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 16:14, 2 December 2015
Crystal structure of the E267V mutant of cytochrome P450 BM3
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