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Arginase

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== Function ==
== Function ==
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'''Arginase''' (Arg) catalyzes the conversion of arginine to ornithine and urea. Arg is the final enzyme in the urea cycle. Arg requires 2 manganese ions for functioning.
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'''Arginase''' (Arg) catalyzes the conversion of arginine to ornithine and urea. Arg is the final enzyme in the urea cycle. Arg requires 2 manganese ions for functioning.<ref>PMID:18360740</ref>
== Disease ==
== Disease ==

Revision as of 11:03, 3 December 2015

Structure of rat arginase containing Mn+2 (purple) complex with ornithine (cyan) and urea (yellow) (PDB code 1hqg).

Drag the structure with the mouse to rotate

3D structures of arginase

Updated on 03-December-2015



References

  1. Dowling DP, Di Costanzo L, Gennadios HA, Christianson DW. Evolution of the arginase fold and functional diversity. Cell Mol Life Sci. 2008 Jul;65(13):2039-55. doi: 10.1007/s00018-008-7554-z. PMID:18360740 doi:http://dx.doi.org/10.1007/s00018-008-7554-z

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Michal Harel, Alexander Berchansky

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