Adenosine A2A receptor
From Proteopedia
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== Function == | == Function == | ||
| - | '''Adenosine A2A receptor''' (A2AR) is one of the G protein-coupled receptors. The protein uses adenosine as the preferred endogenous agonist and is involved in increasing intracellular cAMP levels. | + | '''Adenosine A2A receptor''' (A2AR) is one of the G protein-coupled receptors. The protein uses adenosine as the preferred endogenous agonist and is involved in increasing intracellular cAMP levels.<ref>PMID:21593763</ref> |
== Disease == | == Disease == | ||
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== References == | == References == | ||
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Revision as of 11:50, 3 December 2015
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3D Structures of adenosine A2A receptor
Updated on 03-December-2015
3eml – hA2AR/lysozyme + antagonist – human
3qak – hA2AR/lysozyme + agonist
2ydo – hA2AR (mutant) + adenosine
2ydv – hA2AR (mutant) + agonist
3pwh, 3rey, 3rfm, 3uza, 3uzc – hA2AR (mutant) + antagonist
3vg9, 3vga – hA2AR (mutant) + antibody
4eiy – hA2AR/cytochrome b562 + antagonist
References
- ↑ Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG, Tate CG. Agonist-bound adenosine A(2A) receptor structures reveal common features of GPCR activation. Nature. 2011 May 18. PMID:21593763 doi:10.1038/nature10136
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Nina Clavio, Joel L. Sussman
