This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Adapter molecule crk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
<StructureSection load='1cka' size='350' side='right' caption='Structure of mouse Crk N terminal SH3 domain (grey) complex with proline-rich peptide (green) (PDB entry [[1cka]])' scene='57/573988/Cv/1'>
+
<StructureSection load='1cka' size='350' side='right' caption='Structure of mouse Crk N terminal SH3 domain (magenta) complex with proline-rich peptide (green) (PDB entry [[1cka]])' scene='57/573988/Cv/1'>
== Function ==
== Function ==
Line 7: Line 7:
== Structural highlights ==
== Structural highlights ==
-
Crk domains include several N-terminal SH2 and C-terminal SH3 domains.
+
Crk domains include several N-terminal SH2 and C-terminal SH3 domains. Mouse Crk N terminal SH3 domain complex with proline-rich peptide ([[1cka]]) is shown.
</StructureSection>
</StructureSection>

Revision as of 16:16, 3 December 2015

Structure of mouse Crk N terminal SH3 domain (magenta) complex with proline-rich peptide (green) (PDB entry 1cka)

Drag the structure with the mouse to rotate

3D structures of adpter molecule crk

1m30, 1m3a, 1m3b, 1m3c – mCrk N terminal SH3 (mutant) – mouse - NMR
2ggr – mCrk C terminal SH3 - NMR
2l3p, 2l3q, 2l3s – Crk residues 220-297 – chicken – NMR
1cka, 1ckb – mCrk N terminal SH3 + proline-rich peptide
1b07 – mCrk N terminal SH3 + SH3 peptoid inhibitor
1ju5 – hCrk SH2 + phosphopeptide + Abl SH3 - human

References

  1. ↑ Collins BM, McCoy AJ, Kent HM, Evans PR, Owen DJ. Molecular architecture and functional model of the endocytic AP2 complex. Cell. 2002 May 17;109(4):523-35. PMID:12086608

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Adapter_molecule_crk"
Personal tools