Carbonyl reductase
From Proteopedia
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| - | <StructureSection load='1cyd' size=' | + | <StructureSection load='1cyd' size='350' side='right' scene='48/489333/Cv/1' caption='Mouse carbonyl reductase tetramer complex with 2-propanol and NADPH, [[1cyd]]'> |
'''Carbonyl reductase''' (CBR) catalyzes the reaction converting R-CHOH-R and NADP to R-CO-R’ and NADPH. CBR has wide substrate specificity oxidoreductase activity. CBR has similar properties to aldose reductase and aldehyde reductase. (R)-specific carbonyl reductase cofactor is Zn+2 ion.<ref>PMID:11154733</ref> | '''Carbonyl reductase''' (CBR) catalyzes the reaction converting R-CHOH-R and NADP to R-CO-R’ and NADPH. CBR has wide substrate specificity oxidoreductase activity. CBR has similar properties to aldose reductase and aldehyde reductase. (R)-specific carbonyl reductase cofactor is Zn+2 ion.<ref>PMID:11154733</ref> | ||
Revision as of 07:57, 6 December 2015
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3D structures of carbonyl reductase
Updated on 06-December-2015
References
- ↑ Forrest GL, Gonzalez B. Carbonyl reductase. Chem Biol Interact. 2000 Dec 1;129(1-2):21-40. PMID:11154733
- ↑ Tanaka N, Nonaka T, Nakanishi M, Deyashiki Y, Hara A, Mitsui Y. Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family. Structure. 1996 Jan 15;4(1):33-45. PMID:8805511
