2bl2
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2BL2 is a | + | 2BL2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_hirae Enterococcus hirae] with NA, LHG and UMQ as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] Structure known Active Site: . Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BL2 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: v-type atpase]] | [[Category: v-type atpase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 15:02:20 2007'' |
Revision as of 12:57, 5 November 2007
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THE MEMBRANE ROTOR OF THE V-TYPE ATPASE FROM ENTEROCOCCUS HIRAE
Overview
The membrane rotor ring from the vacuolar-type (V-type) sodium ion-pumping, adenosine triphosphatase (Na+-ATPase) from Enterococcus hirae consists of, 10 NtpK subunits, which are homologs of the 16-kilodalton and 8-kilodalton, proteolipids found in other V-ATPases and in F1Fo- or F-ATPases, respectively. Each NtpK subunit has four transmembrane alpha helices, with, a sodium ion bound between helices 2 and 4 at a site buried deeply in the, membrane that includes the essential residue glutamate-139. This site is, probably connected to the membrane surface by two half-channels in subunit, NtpI, against which the ring rotates. Symmetry mismatch between the rotor, and catalytic domains appears to be an intrinsic feature of both V- and, F-ATPases.
About this Structure
2BL2 is a Single protein structure of sequence from Enterococcus hirae with NA, LHG and UMQ as ligands. Active as H(+)-transporting two-sector ATPase, with EC number 3.6.3.14 Structure known Active Site: . Full crystallographic information is available from OCA.
Reference
Structure of the rotor of the V-Type Na+-ATPase from Enterococcus hirae., Murata T, Yamato I, Kakinuma Y, Leslie AG, Walker JE, Science. 2005 Apr 29;308(5722):654-9. Epub 2005 Mar 31. PMID:15802565
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