Core-binding factor
From Proteopedia
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Mutations in CBF β are implicated in breast cancer. Rearrangements of CBF α and β genes are implicated in acute myeloid leukemia. | Mutations in CBF β are implicated in breast cancer. Rearrangements of CBF α and β genes are implicated in acute myeloid leukemia. | ||
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== Structural highlights == | == Structural highlights == | ||
Revision as of 11:16, 14 December 2015
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3D Structures of core-binding factor
Updated on 14-December-2015
References
- ↑ Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264
