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Core-binding factor

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<StructureSection load='1h9d' size='340' side='right' caption='Human CBFα runt domain (grey and pink) complex with CBFβ heterodimerization domain (green and yellow) and DNA (PDB code [[1h9d]])' scene=''>
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<StructureSection load='1h9d' size='340' side='right' caption='Human CBFα runt domain (magenta) complex with CBFβ heterodimerization domain (green) and DNA (PDB code [[1h9d]])' scene='70/708082/Cv/1'>
== Function ==
== Function ==

Revision as of 08:44, 21 December 2015

Human CBFα runt domain (magenta) complex with CBFβ heterodimerization domain (green) and DNA (PDB code 1h9d)

Drag the structure with the mouse to rotate

3D Structures of core-binding factor

Updated on 21-December-2015


References

  1. Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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