Death-associated protein kinase
From Proteopedia
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== Function == | == Function == | ||
| - | '''Death-associated protein kinase''' (DAPK) is a multi-domain serine/threonine kinase which regulates cell death mechanisms and has tumor suppression functions. <br /> | + | '''Death-associated protein kinase''' (DAPK) is a multi-domain serine/threonine kinase which regulates cell death mechanisms and has tumor suppression functions.<ref>PMID:16756490</ref> <br /> |
* '''DAPK1''' is a positive mediator of γ-interferon induced programmed cell death. <br /> | * '''DAPK1''' is a positive mediator of γ-interferon induced programmed cell death. <br /> | ||
* '''DAPK2''' is a calcium/calmodulin dependent kinase involved in multiple cell signaling pathways which trigger cell survival. <br /> | * '''DAPK2''' is a calcium/calmodulin dependent kinase involved in multiple cell signaling pathways which trigger cell survival. <br /> | ||
Revision as of 09:04, 22 December 2015
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3D structures of death-associated protein kinase
Updated on 22-December-2015
References
- ↑ Bialik S, Kimchi A. The death-associated protein kinases: structure, function, and beyond. Annu Rev Biochem. 2006;75:189-210. PMID:16756490 doi:http://dx.doi.org/10.1146/annurev.biochem.75.103004.142615
