Death-associated protein kinase
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load='1jkl' size=' | + | <StructureSection load='1jkl' size='350' side='right' caption='Structure of human death-associated protein kinase 1 catalytic domain complex with ATP analog (PDB entry [[1jkl]])' scene=''> |
== Function == | == Function == | ||
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== Relevance == | == Relevance == | ||
| - | DAPK expression is lost in many types of cancer. DAPK1 expression is elevated in brains of Alzheimer Disease patients. | + | DAPK expression is lost in many types of cancer. DAPK1 expression is elevated in brains of Alzheimer Disease patients. DAPK1 inhibitors are tested as drugs for attenuating acute brain injury. |
</StructureSection> | </StructureSection> | ||
Revision as of 09:26, 22 December 2015
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3D structures of death-associated protein kinase
Updated on 22-December-2015
References
- ↑ Bialik S, Kimchi A. The death-associated protein kinases: structure, function, and beyond. Annu Rev Biochem. 2006;75:189-210. PMID:16756490 doi:http://dx.doi.org/10.1146/annurev.biochem.75.103004.142615
