DNA methyltransferase

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<StructureSection load='4fsx' size='350' side='right' caption='Mouse cytosine DNMT complex with SAM and Zn+2 ion (grey) (PDB code [[3av6]]).' scene=''>
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<StructureSection load='1nw5' size='350' side='right' caption='Adenine DNMT complex with SAM (PDB code [[1nw5]]).' scene=''>
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== Function ==
== Function ==

Revision as of 14:37, 31 December 2015

Adenine DNMT complex with SAM (PDB code 1nw5).

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3D Structures of DNA methyltransferase

Updated on 31-December-2015

References

  1. Kaina B, Christmann M, Naumann S, Roos WP. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents. DNA Repair (Amst). 2007 Aug 1;6(8):1079-99. Epub 2007 May 7. PMID:17485253 doi:http://dx.doi.org/10.1016/j.dnarep.2007.03.008
  2. Kumar S, Cheng X, Klimasauskas S, Mi S, Posfai J, Roberts RJ, Wilson GG. The DNA (cytosine-5) methyltransferases. Nucleic Acids Res. 1994 Jan 11;22(1):1-10. PMID:8127644
  3. Thomas CB, Scavetta RD, Gumport RI, Churchill ME. Structures of liganded and unliganded RsrI N6-adenine DNA methyltransferase: a distinct orientation for active cofactor binding. J Biol Chem. 2003 Jul 11;278(28):26094-101. Epub 2003 May 4. PMID:12732637 doi:http://dx.doi.org/10.1074/jbc.M303751200

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