Elongation factor
From Proteopedia
(Difference between revisions)
Line 12: | Line 12: | ||
* '''EF-P''' alters the ribosome affinity to aminoacyl-tRNA.<br /> | * '''EF-P''' alters the ribosome affinity to aminoacyl-tRNA.<br /> | ||
* '''EF-1 γ''' acts during the delivery of aminoacyl tRNA to the ribosome.<br /> | * '''EF-1 γ''' acts during the delivery of aminoacyl tRNA to the ribosome.<br /> | ||
- | * '''EF-2''' promotes the translocation of the nascent protein chain from the A site to the P site on the ribosome.<br /> | + | * '''EF-2''' promotes the translocation of the nascent protein chain from the A site to the P site on the ribosome<ref>PMID:16246167</ref>.<br /> |
* '''EF-3''' is a unique EF in fungi hence it provides an anti-fungal drug target.<br /> | * '''EF-3''' is a unique EF in fungi hence it provides an anti-fungal drug target.<br /> | ||
* '''EF Spt4, Spt5, Spt6''' are conserved among eukaryotes. They modulate the chromatin structure.<br /> | * '''EF Spt4, Spt5, Spt6''' are conserved among eukaryotes. They modulate the chromatin structure.<br /> | ||
Line 237: | Line 237: | ||
**[[2fnj]] - mEloBC + GUSTAVUS | **[[2fnj]] - mEloBC + GUSTAVUS | ||
}} | }} | ||
+ | == References == | ||
+ | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Revision as of 14:34, 19 January 2016
|
3D structures of elongation factor
Updated on 19-January-2016
References
- ↑ Jorgensen R, Merrill AR, Andersen GR. The life and death of translation elongation factor 2. Biochem Soc Trans. 2006 Feb;34(Pt 1):1-6. PMID:16246167 doi:http://dx.doi.org/10.1042/BST20060001