Elongation factor

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* '''EF-P''' alters the ribosome affinity to aminoacyl-tRNA.<br />
* '''EF-P''' alters the ribosome affinity to aminoacyl-tRNA.<br />
* '''EF-1 γ''' acts during the delivery of aminoacyl tRNA to the ribosome.<br />
* '''EF-1 γ''' acts during the delivery of aminoacyl tRNA to the ribosome.<br />
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* '''EF-2''' promotes the translocation of the nascent protein chain from the A site to the P site on the ribosome.<br />
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* '''EF-2''' promotes the translocation of the nascent protein chain from the A site to the P site on the ribosome<ref>PMID:16246167</ref>.<br />
* '''EF-3''' is a unique EF in fungi hence it provides an anti-fungal drug target.<br />
* '''EF-3''' is a unique EF in fungi hence it provides an anti-fungal drug target.<br />
* '''EF Spt4, Spt5, Spt6''' are conserved among eukaryotes. They modulate the chromatin structure.<br />
* '''EF Spt4, Spt5, Spt6''' are conserved among eukaryotes. They modulate the chromatin structure.<br />
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**[[2fnj]] - mEloBC + GUSTAVUS
**[[2fnj]] - mEloBC + GUSTAVUS
}}
}}
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== References ==
 +
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 14:34, 19 January 2016

Structure of EF-Tu (grey and pink) with EF-Ts (green and yellow) (PDB entry 1efu)

Drag the structure with the mouse to rotate

3D structures of elongation factor

Updated on 19-January-2016

References

  1. Jorgensen R, Merrill AR, Andersen GR. The life and death of translation elongation factor 2. Biochem Soc Trans. 2006 Feb;34(Pt 1):1-6. PMID:16246167 doi:http://dx.doi.org/10.1042/BST20060001

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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