Enoyl-CoA hydratase

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== Function ==
== Function ==
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'''Enoyl-CoA hydratase''' (ECH) is part of the fatty acid metabolism. ECH hydrates the double bond between the second and third carbons in acyl-CoA. ECH1 or short-chain ECH is mitochondrial. ECH1 processes enoyl-CoA thioesters from C4 to C16.
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'''Enoyl-CoA hydratase''' (ECH) is part of the fatty acid metabolism. ECH hydrates the double bond between the second and third carbons in acyl-CoA. ECH1 or short-chain ECH is mitochondrial. ECH1 processes enoyl-CoA thioesters from C4 to C16<ref>PMID:12467702</ref>.
== Disease ==
== Disease ==

Revision as of 16:19, 19 January 2016

Structure of enoyl-CoA hydratase/isomerase complex with acetoacetyl-CoA and sulfate (PDB code 4fn8).

Drag the structure with the mouse to rotate

3D structures of enoyl-CoA hydratase

Updated on 19-January-2016


References

  1. Agnihotri G, Liu HW. Enoyl-CoA hydratase. reaction, mechanism, and inhibition. Bioorg Med Chem. 2003 Jan 2;11(1):9-20. PMID:12467702

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Michal Harel, Alexander Berchansky

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