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Ephrin receptor
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[[Image:3hei.png|left|200px|thumb|Crystal Structure of ephrin A2 receptor complex with ephrin, [[3hei]]]] | [[Image:3hei.png|left|200px|thumb|Crystal Structure of ephrin A2 receptor complex with ephrin, [[3hei]]]] | ||
{{STRUCTURE_3fxx| PDB=3fxx | SIZE=300| SCENE= |right|CAPTION=Human ephrin A3 receptor (grey) complex with peptide substrate (green), nucleotide derivative (stick model) and Mg+2 ion [[3fxx]] }} | {{STRUCTURE_3fxx| PDB=3fxx | SIZE=300| SCENE= |right|CAPTION=Human ephrin A3 receptor (grey) complex with peptide substrate (green), nucleotide derivative (stick model) and Mg+2 ion [[3fxx]] }} | ||
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Revision as of 18:06, 19 January 2016
Ephrin receptors (EPHR) are components of the cell signaling pathways. They belong to the receptor tyrosine kinases. The extracellular ligand-binding domain (LBD) interacts with ephrin. EPHR domains include an ectodomain (residues 23-435) containing the LBD (residues 23-326), a second fibronectin III domain (fn3) (residues 446-539), a transmembrane domain (residues 539-563), a kinase domain (residues 596-900) and a sterile-α-motif (SAM) domain (residues 908-972). For more details see Ephrin Type-A Receptor.
3D Structures of ephrin receptors
Updated on 19-January-2016
