This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4d4j
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==human PFKFB3 in complex with a pyrrolopyrimidone compound== |
| - | + | <StructureSection load='4d4j' size='340' side='right' caption='[[4d4j]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4d4j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D4J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D4J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BKI:5-(4-BROMOPHENYL)-7-PHENYL-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>BKI</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d4k|4d4k]], [[4d4l|4d4l]], [[4d4m|4d4m]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d4j OCA], [http://pdbe.org/4d4j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d4j RCSB], [http://www.ebi.ac.uk/pdbsum/4d4j PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN]] Synthesis and degradation of fructose 2,6-bisphosphate. |
| - | [[ | + | __TOC__ |
| - | [ | + | </StructureSection> |
| - | [ | + | [[Category: Bennett, N]] |
| - | [ | + | |
| - | + | ||
| - | [[ | + | |
| - | [[Category: | + | |
[[Category: Critchlow, S]] | [[Category: Critchlow, S]] | ||
| + | [[Category: Davies, G]] | ||
| + | [[Category: Debreczeni, J E]] | ||
| + | [[Category: Evans, N]] | ||
| + | [[Category: Holdgate, G]] | ||
| + | [[Category: Jones, N P]] | ||
| + | [[Category: Leach, L]] | ||
[[Category: Maman, S]] | [[Category: Maman, S]] | ||
| - | [[Category: | + | [[Category: McLoughlin, S]] |
| - | [[Category: | + | [[Category: Preston, M]] |
| - | [[Category: | + | [[Category: Rigoreau, L]] |
| + | [[Category: Stgallay, S A]] | ||
| + | [[Category: Thomas, A]] | ||
| + | [[Category: Walker, G]] | ||
[[Category: Walsch, J]] | [[Category: Walsch, J]] | ||
| - | [[Category: | + | [[Category: Ward, R A]] |
| - | [[Category: | + | [[Category: Wheatley, E]] |
[[Category: Winter, J]] | [[Category: Winter, J]] | ||
| - | [[Category: | + | [[Category: Oncology]] |
| + | [[Category: Sugar kinase]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Warburg effect]] | ||
Revision as of 17:08, 20 January 2016
human PFKFB3 in complex with a pyrrolopyrimidone compound
| |||||||||||
Categories: Bennett, N | Critchlow, S | Davies, G | Debreczeni, J E | Evans, N | Holdgate, G | Jones, N P | Leach, L | Maman, S | McLoughlin, S | Preston, M | Rigoreau, L | Stgallay, S A | Thomas, A | Walker, G | Walsch, J | Ward, R A | Wheatley, E | Winter, J | Oncology | Sugar kinase | Transferase | Warburg effect
