4xil

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m (Protected "4xil" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with MPD as the cryoprotectant==
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<StructureSection load='4xil' size='340' side='right' caption='[[4xil]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4xil is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4xil]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XIL FirstGlance]. <br>
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Authors: Brear, P.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
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Description:
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xil OCA], [http://pdbe.org/4xil PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xil RCSB], [http://www.ebi.ac.uk/pdbsum/4xil PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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__TOC__
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</StructureSection>
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[[Category: Exo-alpha-sialidase]]
[[Category: Brear, P]]
[[Category: Brear, P]]
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[[Category: Allosteric inhibitor]]
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[[Category: Crystallization artefact]]
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[[Category: Drug design]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Intramolecular trans-sialidase]]
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[[Category: Neuraminidase]]
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[[Category: Serendipitous allosteric site]]

Revision as of 17:12, 20 January 2016

Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with MPD as the cryoprotectant

4xil, resolution 1.90Å

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