This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5hel

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5hel" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
+
==Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2==
-
 
+
<StructureSection load='5hel' size='340' side='right' caption='[[5hel]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
-
The entry 5hel is ON HOLD
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5hel]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HEL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HEL FirstGlance]. <br>
-
Authors: Tallant, C., Lori, C., Pasquo, A., Chiaraluce, R., Consalvi, V., Newman, J.A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hel OCA], [http://pdbe.org/5hel PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hel RCSB], [http://www.ebi.ac.uk/pdbsum/5hel PDBsum]</span></td></tr>
-
Description: Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2
+
</table>
-
[[Category: Unreleased Structures]]
+
== Function ==
-
[[Category: Pasquo, A]]
+
[[http://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
-
[[Category: Lori, C]]
+
== References ==
-
[[Category: Knapp, S]]
+
<references/>
-
[[Category: Chiaraluce, R]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]
 +
[[Category: Chiaraluce, R]]
[[Category: Consalvi, V]]
[[Category: Consalvi, V]]
-
[[Category: Arrowsmith, C.H]]
+
[[Category: Delft, F von]]
-
[[Category: Von Delft, F]]
+
[[Category: Edwards, A M]]
-
[[Category: Edwards, A.M]]
+
[[Category: Knapp, S]]
-
[[Category: Newman, J.A]]
+
[[Category: Lori, C]]
 +
[[Category: Newman, J A]]
 +
[[Category: Pasquo, A]]
[[Category: Tallant, C]]
[[Category: Tallant, C]]
 +
[[Category: Post translational modifications recognition]]
 +
[[Category: Transcription]]
 +
[[Category: Transcription regulation]]

Revision as of 17:28, 20 January 2016

Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2

5hel, resolution 1.45Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5hel"
Personal tools