Formate dehydrogenase
From Proteopedia
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| - | '''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either NAD+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The Mo-dependent FDH-H from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub>. | + | '''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either NAD+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The Mo-dependent FDH-H from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>. |
==3D structure of formate dehydrogenase== | ==3D structure of formate dehydrogenase== | ||
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**[[1h0h]] - FDH + Fe4S4 +MGD – ''Desulfovibrio gigas'' | **[[1h0h]] - FDH + Fe4S4 +MGD – ''Desulfovibrio gigas'' | ||
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| + | == References == | ||
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[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 22:34, 22 January 2016
Template:STRUCTURE 2nad Formate dehydrogenase (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either NAD+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe4S4 center and then to cytochrome. The Mo-dependent FDH-H from E. coli contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe4S4[1].
3D structure of formate dehydrogenase
Updated on 22-January-2016
