4xuj
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==X-ray structure of NCP containing RuII-arene complex of thiomorpholine substituted 3-Hydroxy-2-pyridone ligands== |
| - | + | <StructureSection load='4xuj' size='340' side='right' caption='[[4xuj]], [[Resolution|resolution]] 3.18Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xuj]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XUJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4A6:[(1,2,3,4,5,6-ETA)-1-METHYL-4-(PROPAN-2-YL)BENZENE]RUTHENIUM'>4A6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xuj OCA], [http://pdbe.org/4xuj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xuj RCSB], [http://www.ebi.ac.uk/pdbsum/4xuj PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H32_XENLA H32_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Adhireksan, Z]] | [[Category: Adhireksan, Z]] | ||
| - | [[Category: Davey, C | + | [[Category: Davey, C A]] |
| + | [[Category: Dna-bindig protein-dna complex]] | ||
| + | [[Category: Dna-binding protein-dna complex]] | ||
| + | [[Category: Nucleosome]] | ||
| + | [[Category: Ruthenium agent]] | ||
Revision as of 02:30, 28 January 2016
X-ray structure of NCP containing RuII-arene complex of thiomorpholine substituted 3-Hydroxy-2-pyridone ligands
| |||||||||||
