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2g06

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<StructureSection load='2g06' size='340' side='right' caption='[[2g06]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='2g06' size='340' side='right' caption='[[2g06]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2g06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G06 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2g06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G06 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PIN:PIPERAZINE-N,N-BIS(2-ETHANESULFONIC+ACID)'>PIN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PIN:PIPERAZINE-N,N-BIS(2-ETHANESULFONIC+ACID)'>PIN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bdu|2bdu]], [[2g07|2g07]], [[2g08|2g08]], [[2g09|2g09]], [[2g0a|2g0a]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bdu|2bdu]], [[2g07|2g07]], [[2g08|2g08]], [[2g09|2g09]], [[2g0a|2g0a]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nt5c3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nt5c3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g06 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g06 RCSB], [http://www.ebi.ac.uk/pdbsum/2g06 PDBsum], [http://www.topsan.org/Proteins/CESG/2g06 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g06 OCA], [http://pdbe.org/2g06 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g06 RCSB], [http://www.ebi.ac.uk/pdbsum/2g06 PDBsum], [http://www.topsan.org/Proteins/CESG/2g06 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/5NT3_MOUSE 5NT3_MOUSE]] Can act both as nucleotidase and as phosphotransferase (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g06 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2g06" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: 5'-nucleotidase]]
[[Category: 5'-nucleotidase]]
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[[Category: Mus musculus]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Bingman, C A.]]
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[[Category: Bingman, C A]]
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[[Category: Bitto, E.]]
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[[Category: Bitto, E]]
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Phillips, G N.]]
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[[Category: Phillips, G N]]
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[[Category: Wesenberg, G E.]]
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[[Category: Wesenberg, G E]]
[[Category: Aah38029]]
[[Category: Aah38029]]
[[Category: Bc038029]]
[[Category: Bc038029]]
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[[Category: Center for eukaryotic structural genomic]]
 
[[Category: Cesg]]
[[Category: Cesg]]
[[Category: Cytosolic 5'-nucleotidase iii]]
[[Category: Cytosolic 5'-nucleotidase iii]]
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[[Category: Nt5c3 protein]]
[[Category: Nt5c3 protein]]
[[Category: P5n-1]]
[[Category: P5n-1]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyrimidine 5'-nucleotidase 1]]
[[Category: Pyrimidine 5'-nucleotidase 1]]
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[[Category: Structural genomics functional follow-up study]]
 
[[Category: Umph-1]]
[[Category: Umph-1]]
[[Category: Uniprot q9d020]]
[[Category: Uniprot q9d020]]

Current revision

X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, with bound magnesium(II)

2g06, resolution 2.25Å

Drag the structure with the mouse to rotate

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