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1dc0
From Proteopedia
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|PDB= 1dc0 |SIZE=350|CAPTION= <scene name='initialview01'>1dc0</scene>, resolution 1.3Å | |PDB= 1dc0 |SIZE=350|CAPTION= <scene name='initialview01'>1dc0</scene>, resolution 1.3Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dc0 OCA], [http://www.ebi.ac.uk/pdbsum/1dc0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dc0 RCSB]</span> | ||
}} | }} | ||
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[[Category: intermediate]] | [[Category: intermediate]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:38:35 2008'' |
Revision as of 16:38, 30 March 2008
| |||||||
| , resolution 1.3Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG
Overview
The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 A has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a backbone-centered mechanism for the A <--> B transition mediated by guanine tracts. Interconversion between A and B DNA provides another means for regulating protein-DNA recognition.
About this Structure
1DC0 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
The structure of a stable intermediate in the A <--> B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:10688897
Page seeded by OCA on Sun Mar 30 19:38:35 2008
