1dul
From Proteopedia
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|PDB= 1dul |SIZE=350|CAPTION= <scene name='initialview01'>1dul</scene>, resolution 1.80Å | |PDB= 1dul |SIZE=350|CAPTION= <scene name='initialview01'>1dul</scene>, resolution 1.80Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> | + | |LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=CCC:CYTIDINE-5'-PHOSPHATE-2',3'-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dul OCA], [http://www.ebi.ac.uk/pdbsum/1dul PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dul RCSB]</span> | ||
}} | }} | ||
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[[Category: Rambo, R P.]] | [[Category: Rambo, R P.]] | ||
[[Category: Rha, B.]] | [[Category: Rha, B.]] | ||
| - | [[Category: K]] | ||
| - | [[Category: MG]] | ||
[[Category: double helix]] | [[Category: double helix]] | ||
[[Category: internal loop]] | [[Category: internal loop]] | ||
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[[Category: tetraloop]] | [[Category: tetraloop]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:49:01 2008'' |
Revision as of 16:49, 30 March 2008
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| , resolution 1.80Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE
Overview
The signal recognition particle (SRP), a protein-RNA complex conserved in all three kingdoms of life, recognizes and transports specific proteins to cellular membranes for insertion or secretion. We describe here the 1.8 angstrom crystal structure of the universal core of the SRP, revealing protein recognition of a distorted RNA minor groove. Nucleotide analog interference mapping demonstrates the biological importance of observed interactions, and genetic results show that this core is functional in vivo. The structure explains why the conserved residues in the protein and RNA are required for SRP assembly and defines a signal sequence recognition surface composed of both protein and RNA.
About this Structure
1DUL is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of the ribonucleoprotein core of the signal recognition particle., Batey RT, Rambo RP, Lucast L, Rha B, Doudna JA, Science. 2000 Feb 18;287(5456):1232-9. PMID:10678824
Page seeded by OCA on Sun Mar 30 19:49:01 2008
