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Enzymes: enzyme-substrate complex
From Proteopedia
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| - | [[es:Enzymes: enzyme-substrate complex ( | + | [[es:Enzymes: enzyme-substrate complex (Spanish)]] |
<Structure load='4ald' size='800' frame='true' align='right' caption='Fructosa-bifosfato aldolasa (PDB [[4ald]])' scene='60/603296/F2pa/4' /> | <Structure load='4ald' size='800' frame='true' align='right' caption='Fructosa-bifosfato aldolasa (PDB [[4ald]])' scene='60/603296/F2pa/4' /> | ||
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:::*Enzyme: '''Fructose biphosphate aldolase''' | :::*Enzyme: '''Fructose biphosphate aldolase''' | ||
:::*Substrate: '''fructose-1,6-biphosphate''' | :::*Substrate: '''fructose-1,6-biphosphate''' | ||
| - | :::*Products: '''glyceraldehyde-3-phosphate''' and '''dihydroxiacetone-phosphate''. | + | :::*Products: '''glyceraldehyde-3-phosphate''' and '''dihydroxiacetone-phosphate'''. |
| - | :::This <scene name='60/603296/F2pa/4'>ribbon model</scene> shows | + | :::This <scene name='60/603296/F2pa/4'>ribbon model</scene> shows secondary structures in '''Fructose biphosphate aldolase''' molecule. |
| - | :::This <scene name='60/603296/F2pa/3'>wireframe model</scene> shows the polypeptide chain skeleton and R groups. | + | :::This <scene name='60/603296/F2pa/3'>wireframe model</scene> shows the polypeptide chain skeleton and amino acids R groups. |
| - | :::The polypeptide chain of this enzyme consist of <scene name='60/603296/F2pa/17'>363 amino acid | + | :::The polypeptide chain of this enzyme consist of <scene name='60/603296/F2pa/17'>363 amino acid residues</scene>. |
| - | :::Now, we are going to <scene name='60/603296/F2pa/5'>soften colors</scene> to highligth enzyme | + | :::Now, we are going to <scene name='60/603296/F2pa/5'>soften colors</scene> to highligth the enzyme <scene name='60/603296/F2pa/6'>active site</scene> |
:::Active site is surrounded by <scene name='60/603296/F2pa/7'>9 amino acid residues</scene> | :::Active site is surrounded by <scene name='60/603296/F2pa/7'>9 amino acid residues</scene> | ||
:::<scene name='60/603296/F2pa/9'>Substrate molecule</scene>, i.e., '''fructose-1,6-biphosphate'''. fits into active site. | :::<scene name='60/603296/F2pa/9'>Substrate molecule</scene>, i.e., '''fructose-1,6-biphosphate'''. fits into active site. | ||
Current revision
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- Enzyme: Fructose biphosphate aldolase
- Substrate: fructose-1,6-biphosphate
- Products: glyceraldehyde-3-phosphate and dihydroxiacetone-phosphate.
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- This shows secondary structures in Fructose biphosphate aldolase molecule.
- This shows the polypeptide chain skeleton and amino acids R groups.
- The polypeptide chain of this enzyme consist of .
- Now, we are going to to highligth the enzyme
- Active site is surrounded by
- , i.e., fructose-1,6-biphosphate. fits into active site.
- In this , fit between active site and substrate is best seen.
- Zoom out to see a whole view.
- All models we have analyzed show a of fructose biphosphate aldolase. Really, this enzyme is a oligomeric protein composed of four subunits that perform a .
References
This page is based on the Proteopedia file 4ald.
