Poly(A) RNA polymerase
From Proteopedia
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<StructureSection load='4e80' size='340' side='right' caption='Cid1 complex with UTP (stick model) (PDB code [[4e80]])' scene=''> | <StructureSection load='4e80' size='340' side='right' caption='Cid1 complex with UTP (stick model) (PDB code [[4e80]])' scene=''> | ||
| - | '''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis. Cid1 is found in fission yeast. Cid1 exists in 3 forms: apo I consists of 4 subunits; apo II consists of 2 subunits; UTP-bound form consists of 4 subunits. The UTP-bound form has in its N-terminal domain a catalytic triad of Asp residues which binds the UTP. | ||
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== Function == | == Function == | ||
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| + | '''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis. Cid1 is found in fission yeast. Cid1 exists in 3 forms: apo I consists of 4 subunits; apo II consists of 2 subunits; UTP-bound form consists of 4 subunits. The UTP-bound form has in its N-terminal domain a catalytic triad of Asp residues which binds the UTP. | ||
== Disease == | == Disease == | ||
Revision as of 08:46, 18 February 2016
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3D Structures of poly(A) RNA polymerase protein Cid1
Updated on 18-February-2016
4e7x, 4e8f – Cid1
4ud4, 4ud5 – Cid1 (mutant)
4e80 – Cid1 + UTP
4fh3 – Cid1 residues 33-377
4ep7, 4fh5, 4fhp – Cid1 residues 30-377 + UTP
4fhv – Cid1 residues 30-377 + CTP
4fhw – Cid1 residues 30-377 + GTP
4fhy – Cid1 residues 30-377 + ATP
4fhx – Cid1 residues 30-377 (mutant) + ATP
4nkt – Cid1 residues 30-377 + UMPNPP
4nku – Cid1 residues 40-377 (mutant) + dinucleotide
References
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