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5heg
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Pentameric ligand-gated ion channel GLIC mutant P246G== | |
| - | + | <StructureSection load='5heg' size='340' side='right' caption='[[5heg]], [[Resolution|resolution]] 3.21Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5heg]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HEG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HEG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ehz|3ehz]]</td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5heg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5heg OCA], [http://pdbe.org/5heg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5heg RCSB], [http://www.ebi.ac.uk/pdbsum/5heg PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bertozzi, C]] | [[Category: Bertozzi, C]] | ||
[[Category: Dtuzler, R]] | [[Category: Dtuzler, R]] | ||
| + | [[Category: Hilf, R J.C]] | ||
| + | [[Category: Ligand-gated ion channel]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Pentameric ligand-gated ion channel]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 15:29, 2 March 2016
Pentameric ligand-gated ion channel GLIC mutant P246G
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