Galactose mutarotase
From Proteopedia
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<StructureSection load='1ns0' size='350' side='right' caption='Structure of galactose mutarotase complex with α-D-galactose and Na+ ion (purple) (PDB entry [[1ns0]])' scene=''> | <StructureSection load='1ns0' size='350' side='right' caption='Structure of galactose mutarotase complex with α-D-galactose and Na+ ion (purple) (PDB entry [[1ns0]])' scene=''> | ||
| + | __TOC__ | ||
== Function == | == Function == | ||
'''Galactose mutarotase''' (GalM) reversibly converts α-lactose to β-lactose. GalM catalyzes the first step in galactose metabolism<ref>PMID:12717027</ref>. | '''Galactose mutarotase''' (GalM) reversibly converts α-lactose to β-lactose. GalM catalyzes the first step in galactose metabolism<ref>PMID:12717027</ref>. | ||
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| + | == Structural highlights == | ||
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| + | From extensive study of mutations in ''Lactococcus lactis'' GalM complexes with various sugars it was found that residues H170 and E304 are critical for the active site binding. | ||
== 3D structures of galactose mutarotase == | == 3D structures of galactose mutarotase == | ||
Revision as of 08:08, 3 March 2016
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