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4yc9

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==Crystal structure of TRIM24 PHD-bromodomain complexed with N-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3,4-dimethoxybenzene-1-sulfonamide (8i)==
==Crystal structure of TRIM24 PHD-bromodomain complexed with N-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3,4-dimethoxybenzene-1-sulfonamide (8i)==
<StructureSection load='4yc9' size='340' side='right' caption='[[4yc9]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
<StructureSection load='4yc9' size='340' side='right' caption='[[4yc9]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4C1:N-(6-{3-[4-(DIMETHYLAMINO)BUTOXY]-5-PROPOXYPHENOXY}-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-5-YL)-3,4-DIMETHOXYBENZENESULFONAMIDE'>4C1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4C1:N-(6-{3-[4-(DIMETHYLAMINO)BUTOXY]-5-PROPOXYPHENOXY}-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-5-YL)-3,4-DIMETHOXYBENZENESULFONAMIDE'>4C1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yab|4yab]], [[4yad|4yad]], [[4yat|4yat]], [[4yax|4yax]], [[4ybm|4ybm]], [[4ybs|4ybs]], [[4ybt|4ybt]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yab|4yab]], [[4yad|4yad]], [[4yat|4yat]], [[4yax|4yax]], [[4ybm|4ybm]], [[4ybs|4ybs]], [[4ybt|4ybt]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yc9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yc9 RCSB], [http://www.ebi.ac.uk/pdbsum/4yc9 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yc9 OCA], [http://pdbe.org/4yc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yc9 RCSB], [http://www.ebi.ac.uk/pdbsum/4yc9 PDBsum]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4yc9" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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[[Category: Center for biomolecular structure and function]]
[[Category: Center for biomolecular structure and function]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
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[[Category: Transcription-transcription inhibitor complex]]
[[Category: Trim24]]
[[Category: Trim24]]

Revision as of 19:42, 9 March 2016

Crystal structure of TRIM24 PHD-bromodomain complexed with N-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3,4-dimethoxybenzene-1-sulfonamide (8i)

4yc9, resolution 1.82Å

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